What are causes of renal dysfunction?

What are causes of  renal dysfunction?This is the concern of many patients with renal insufficiency, hospital experts your questions are described in detail the main reason for renal dysfunction.
The main reason for renal insufficiency, including two major aspects: the disease lead to renal dysfunction and drug induced renal dysfunction.
(1) the disease lead to renal failure
Renal insufficiency is the development of kidney disease to late renal partial or complete loss of the pathological state. A variety of chronic kidney disease can lead to renal function decline, and the eventual development of renal insufficiency, renal insufficiency reasons. May lead to chronic renal insufficiency, some chronic diseases, including primary glomerulonephritis, diabetic nephropathy, hypertension, kidney disease, kidney the quality tubule kidney disease, polycystic kidney disease and other illnesses.
(2) drug induced renal dysfunction
Found in a survey of the number of patients with renal insufficiency, inappropriate use of nephrotoxic drugs long-term damage to the kidneys, accumulated up to a certain degree of renal insufficiency. That is an important factor to cause renal dysfunction causes, such as painkillers, analgesic film containing non This cefoxitin taking long-term continue to damage the kidneys, causing chronic interstitial nephritis, and then the development of renal insufficiency; In addition to outside the inappropriate use of gentamicin and other drugs to cause the key to the causes of renal insufficiency.